It took a little research but here is the solution (and its simple) if you come across this issue.
1 - Click on Start –> Control Panel –> (If windows Vista or 7) click View by (on top right) and change to Large Icons –> Click on Folder Options
2 – Click on the View tab (op top) –> In the Advanced Settings Window select “Show hidden files, folders, and drives.**
**In addition, as a general rule I suggest removing the checks next to
- Hide extensions for known file types
- Hide protected operating system files
I recommend these changes as hidden files could be used to hide infections from being seen.
After the changes click OK
- NOW BEFORE STEP 3 – MAKE SURE TWEETDECK IS COMPLETELY CLOSED
3 – Once you have made those changes, click on Start –> My Computer –> or click on the My Computer icon on the desktop.
Look for the following location in the C: \ ->
Windows XP –> C:\Documents and Settings\(Name you are logged in under)\Local Settings\Application Data
Windows 7 / Vista –> C:\Users\(Name you are logged in under)\AppData\Local
– Once you are have reached the Local Folder (Win 7 / Vista) or Application Data Folder (Win XP), look for a folder called Twitter.
Find the folder and delete the folder. What that will do is cause the Sign In Screen to appear again next time you start TweetDeck.
Just sign in and everything should be back to normal.